https://www.ceesdekker.net Secrets

https://www.ceesdekker.net Secrets

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Nanotechnology features a range of possibilities to lead to biology. Listed here I'll current illustrations wherever nanofabrication – the ability to make confined structures with Proportions at will – is used to examine the biophysics of single molecules and cells. I will present some illustrations from our lab:

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Nanofabrication of electrodes with sub-five nm spacing for transport experiments on one molecules and metal clusters

We create stage-of-treatment diagnostics examination of neglected tropical conditions within just source-limited configurations, determined by Crspr/Cas9 detecting of pathogen’s DNA in entire body fluids.

SMC complexes can pass physical roadblocks larger than their ring dimensions, indicating a nontopological mechanism for DNA loop extrusion

Length Charge of particular person carbon nanotubes by nanostructuring Along with the scanning tunneling microscope

2000, discovery that nanotubes can carry incredible big recent densities; fixed the controversial concern of Digital transportation through DNA molecules by measurements of insulating conduct at The one molecule level; and demonstration of an AFM strategy for one-molecule manipulation of nanotubes

In 1993, as being a younger and keen affiliate professor at Delft University of Engineering, I'd in the beginning targeted the investigation endeavours of my team on measuring the electrical conductance of a single conducting-polymer molecule. In two yrs, we experienced created a device during which an individual wire of the phthalocyaninepolysiloxane polymer was related between two closely spaced metal nanoelectrodes.

Resolving the step size in condensin-pushed DNA loop extrusion identifies ATP binding given that the action-making course of action

‘The concept there is such a point being a commencing, a major bang, is already an interesting signpost to contemplate that there was a creator. But far more commonly, and on The premise of pure rationality, I also get there in a Christian interpretation of truth. An atheistic ceesdekker.net worldview is a naturalistic worldview: fundamentally, there are only atoms and all-natural forces that we are able to measure.

Later on we spoke all over again briefly because Dekker felt that our discussion of his faith speedily turned purely philosophical, Whilst it also concretely assists him in his perform.

Let’s very first seem back again in the intervening time after you made a decision to change your aim from superconductivity and nanotubes to biology at the conclusion of the nineteen nineties.

Supercoiling-dependent DNA binding: quantitative modeling and applications to bulk and one-molecule experiments